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Dajana Vuckovic, PhD

  • Professor and Concordia University Research Chair, Chemistry and Biochemistry
  • Director, Centre for Biological Applications of Mass Spectrometry

Contact information

Biography

Education

NSERC PDF (University of Toronto)
PhD (University of Waterloo)

PetroCanada Young Innovator Award

Concordia University

Vuckovic group

Concordia University

Teaching activities

Undergraduate courses

CHEM 218 - Introductory Analytical Chemistry II
CHEM 411 - Advanced Bioanalytical Chemistry
CHEM 498 - Mass Spectrometry in Metabolomics and Proteomics
SCOL 350 - Biomarkers

Graduate courses

CHEM 611 - Advanced Bioanalytical Chemistry
CHEM 614 - Mass Spectrometry in Metabolomics and Proteomics

Publications

Metabolomics

1.  Ben-Porat, T., Alberga, A., Audet, M-C., Belleville, S., Cohen, T., Garneau, P.Y., Lavoie K.L., Marion, P., Mellah, S., Pescarus, R., Rahme, E., Santosa, S., Studer, A-S., Vuckovic, D., Woods, R., Yousefi, R. Bacon S.L. for the EMBRACE Study Team. Understanding the impact of radical changes in diet and the gut microbiota on brain function and structure: Rationale and design of the EMBRACE study. Surgery for Obesity and Related Diseases. 19 (9), 1000-1012 (2023). https://doi.org/10.1016/j.soard.2023.02.022

2. Russo, M., Napylov, A., Paquet, A., Vuckovic, D., Comparison of N-ethyl maleimide and N-(1-phenylethyl) maleimide for derivatization of biological thiols using liquid chromatography-mass spectrometry, Analytical and Bioanalytical Chemistry 412, 1639-1652, (2020).  

https://link.springer.com/article/10.1007/s00216-020-02398-x

3.  Sonnenberg, R., Naz, S., Cougnaud, L., Vuckovic, D., Comparison of underivatized silica and zwitterionic sulfobetaine hydrophilic interaction liquid chromatography stationary phases for global metabolomics of human plasma, Journal of Chromatography A, 1608, 460419, (2019).  https://doi.org/10.1016/j.chroma.2019.460419

4.  Vuckovic, D.  Improving metabolome coverage and data quality: advancing metabolomics and lipidomics for biomarker discovery, Chemical Communications, 54, 6728-6749 (2018, invited feature for Emerging Investigators Issue 2018)https://pubs.rsc.org/en/content/articlelanding/2018/cc/c8cc02592d/

5.  Sitnikov, D., Monnin, C. & Vuckovic D., Systematic Assessment of Seven Solvent and Solid-Phase Extraction Methods for Metabolomics Analysis of Human Plasma by LC-MS, Scientific Reports 6, 38885 (2016).  https://www.nature.com/articles/srep38885


Mycotoxins

1.  Slobodchikova, I., Sivakumar, R., Md Rahman, S., Vuckovic, D. Characterization of phase I and glucuronide phase II metabolites of 17 mycotoxins using liquid chromatography – high-resolution mass spectrometry, Toxins, 11(8), 433, article 11080433, (2019). 

2.  Slobodchikova, I. & Vuckovic, D. Liquid chromatography – high-resolution mass spectrometry method for monitoring of 17 mycotoxins in human plasma for exposure studies, Journal of Chromatography A, 1548, 51-63 (2018).   https://doi.org/10.1016/j.chroma.2018.03.030


Lipidomics

1. Dos Santos, A. C., Vuckovic, D., Current status and advances in tissue lipidomics for cardiovascular and nutritional studies, Trends in Analytical Chemistry, 170, article 117419, (2024).
https://doi.org/10.1016/j.trac.2023.117419

2. Napylov, A., Reyes Garces, N., Gomez-Rios, G., Monnin C., Olkowicz, M., Lendor, S., Bojko, B., Hamani, C., Pawliszyn, J., Vuckovic, D.  In vivo solid-phase microextraction for sampling of oxylipins in brain of awake, moving rats, Angewandte Chemie International Edition 59, 2392-2398, (2020).
https://doi.org/10.1002/anie.201909430

3.  Monnin, C., Ramrup, P., Daigle-Young, C. & Vuckovic D., Improving negative ESI-LC-MS lipidomic analysis of human plasma using acetic acid as a mobile phase additive, Rapid Communications in Mass Spectrometry 32:201-211 (2018, top 20 most-downloaded article of 2017-2018). 
https://doi.org/10.1002/rcm.8024

4. J.A. Bowden, A. Heckert, C.Z. Ulmer, C.M. Jones, J.P. Koelmel, L. Abdullah, … D. Vuckovic, J.M. Weir, R. Welti, M.R. Wenk, C. Wheelock, M. Yuan, X. H. Zhao, & S. Zhou, Harmonizing Lipidomics: NIST Interlaboratory Comparison Exercise for Lipidomics using Standard Reference Material 1950 – Metabolites in Frozen Human Plasma, Journal of Lipid Research 58, 2275-2288 (2017).  
https://doi.org/10.1194/jlr.M079012

Participation activities

Metabolomics Association of North America

https://www.metabolomicsna.org/board-of-directors

The Metabolomics Innovation Centre

https://metabolomicscentre.ca/

Metabolomics Quality Assurance and Quality Control Consortium (mQACC)

https://www.mqacc.org/

Canadian Society for Mass Spectrometry

https://www.csms-scsm.ca/
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