Dajana Vuckovic, PhD

Professor and Concordia University Research Chair, Chemistry and Biochemistry
Director, Centre for Biological Applications of Mass Spectrometry

Research areas: analytical chemistry, metabolomics, lipidomics, mass spectrometry, sample preparation, separation science, bioanalysis, biomarker discovery and validation, inflammation, oxylipins, cardiovascular health, nutrition

Contact information

Email:

dajana.vuckovic@concordia.ca

Websites:

CBAMS
School of Health
Google Scholar

ORCID:

0000-0002-7764-8492

Biography

Education

NSERC PDF (University of Toronto)
PhD (University of Waterloo)

PetroCanada Young Innovator Award

Concordia University

Vuckovic group

Concordia University

Teaching activities

Undergraduate courses

CHEM 218 - Introductory Analytical Chemistry II
CHEM 411 - Advanced Bioanalytical Chemistry
CHEM 498 - Mass Spectrometry in Metabolomics and Proteomics
SCOL 350 - Biomarkers

Graduate courses

CHEM 611 - Advanced Bioanalytical Chemistry
CHEM 614 - Mass Spectrometry in Metabolomics and Proteomics

Publications

Metabolomics

1. Ben-Porat, T., Alberga, A., Audet, M-C., Belleville, S., Cohen, T., Garneau, P.Y., Lavoie K.L., Marion, P., Mellah, S., Pescarus, R., Rahme, E., Santosa, S., Studer, A-S., Vuckovic, D., Woods, R., Yousefi, R. Bacon S.L. for the EMBRACE Study Team. Understanding the impact of radical changes in diet and the gut microbiota on brain function and structure: Rationale and design of the EMBRACE study. Surgery for Obesity and Related Diseases. 19 (9), 1000-1012 (2023). https://doi.org/10.1016/j.soard.2023.02.022

2. Russo, M., Napylov, A., Paquet, A., Vuckovic, D., Comparison of N-ethyl maleimide and N-(1-phenylethyl) maleimide for derivatization of biological thiols using liquid chromatography-mass spectrometry, Analytical and Bioanalytical Chemistry 412, 1639-1652, (2020).

https://link.springer.com/article/10.1007/s00216-020-02398-x

3. Sonnenberg, R., Naz, S., Cougnaud, L., Vuckovic, D., Comparison of underivatized silica and zwitterionic sulfobetaine hydrophilic interaction liquid chromatography stationary phases for global metabolomics of human plasma, Journal of Chromatography A, 1608, 460419, (2019). https://doi.org/10.1016/j.chroma.2019.460419

4. Vuckovic, D. Improving metabolome coverage and data quality: advancing metabolomics and lipidomics for biomarker discovery, Chemical Communications, 54, 6728-6749 (2018, invited feature for Emerging Investigators Issue 2018). https://pubs.rsc.org/en/content/articlelanding/2018/cc/c8cc02592d/

5. Sitnikov, D., Monnin, C. & Vuckovic D., Systematic Assessment of Seven Solvent and Solid-Phase Extraction Methods for Metabolomics Analysis of Human Plasma by LC-MS, Scientific Reports 6, 38885 (2016). https://www.nature.com/articles/srep38885

Mycotoxins

1. Slobodchikova, I., Sivakumar, R., Md Rahman, S., Vuckovic, D. Characterization of phase I and glucuronide phase II metabolites of 17 mycotoxins using liquid chromatography – high-resolution mass spectrometry, Toxins, 11(8), 433, article 11080433, (2019).

2. Slobodchikova, I. & Vuckovic, D. Liquid chromatography – high-resolution mass spectrometry method for monitoring of 17 mycotoxins in human plasma for exposure studies, Journal of Chromatography A, 1548, 51-63 (2018). https://doi.org/10.1016/j.chroma.2018.03.030

Lipidomics

1. Dos Santos, A. C., Vuckovic, D., Current status and advances in tissue lipidomics for cardiovascular and nutritional studies, Trends in Analytical Chemistry, 170, article 117419, (2024).
https://doi.org/10.1016/j.trac.2023.117419

2. Napylov, A., Reyes Garces, N., Gomez-Rios, G., Monnin C., Olkowicz, M., Lendor, S., Bojko, B., Hamani, C., Pawliszyn, J., Vuckovic, D. In vivo solid-phase microextraction for sampling of oxylipins in brain of awake, moving rats, Angewandte Chemie International Edition 59, 2392-2398, (2020).
https://doi.org/10.1002/anie.201909430

3. Monnin, C., Ramrup, P., Daigle-Young, C. & Vuckovic D., Improving negative ESI-LC-MS lipidomic analysis of human plasma using acetic acid as a mobile phase additive, Rapid Communications in Mass Spectrometry 32:201-211 (2018, top 20 most-downloaded article of 2017-2018).
https://doi.org/10.1002/rcm.8024

4. J.A. Bowden, A. Heckert, C.Z. Ulmer, C.M. Jones, J.P. Koelmel, L. Abdullah, … D. Vuckovic, J.M. Weir, R. Welti, M.R. Wenk, C. Wheelock, M. Yuan, X. H. Zhao, & S. Zhou, Harmonizing Lipidomics: NIST Interlaboratory Comparison Exercise for Lipidomics using Standard Reference Material 1950 – Metabolites in Frozen Human Plasma, Journal of Lipid Research 58, 2275-2288 (2017).
https://doi.org/10.1194/jlr.M079012

Participation activities