
Melissa K. Passarelli
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Melissa K. Passarelli, Ph.D.
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Sign in to editResearch areas: Imaging Mass Spectrometry (IMS); Spatial 'omics; Secondary Ion Mass Spectrometry (SIMS); Matrix-Assisted Laser Desorption Ionization (MALDI)
Contact information
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Biography
Education
The Pennsylvania State University (Ph.D.)
Union College (B.Sc.)
Teaching activities
CHEM 212
Analytical Chemistry for Biologist (Winter)
CHEM 498-610
Imaging Mass Spectrometry (Summer)
CHEM 271
Biochemistry
Research activities
Mass Spectrometry-based Intracellular Drug Measurements (FRQNT)
We are developing a multi-modal analytical approach that combined live-cell atomic force microscopy(AFM) and single-cell mass spectrometry (MS) to evaluate intracellular drug levels.
With this multi-modal approach, we will investigate the cellular uptake of pharmaceutical compounds and examine the biochemical effects at therapeutic and toxic levels.

Multi-modal workflow
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