Melissa K. Passarelli, Ph.D.

Research areas: Imaging Mass Spectrometry (IMS); Spatial 'omics; Secondary Ion Mass Spectrometry (SIMS); Matrix-Assisted Laser Desorption Ionization (MALDI)

Contact information

Email:

melissa.passarelli@concordia.ca

Websites:

Google Scholar
Lab webpage

Biography

Education

The Pennsylvania State University (Ph.D.)
Union College (B.Sc.)

Teaching activities

CHEM 212

Analytical Chemistry for Biologist (Winter)

CHEM 498-610

Imaging Mass Spectrometry (Summer)

CHEM 271

Biochemistry

Research activities

Mass Spectrometry-based Intracellular Drug Measurements (FRQNT)

We are developing a multi-modal analytical approach that combined live-cell atomic force microscopy(AFM) and single-cell mass spectrometry (MS) to evaluate intracellular drug levels.

With this multi-modal approach, we will investigate the cellular uptake of pharmaceutical compounds and examine the biochemical effects at therapeutic and toxic levels.

Multi-modal workflow