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Deniz Meneksedag Erol

  • Assistant Professor and Graduate Program Director, Diploma and Certificate Programs, Chemical and Materials Engineering

Research areas: Biomaterials, Nanomaterials, Biomolecular simulations, Computational biophysics, Disordered proteins, Molecular dynamics, Structural biology

Contact information

Biography

Education

PhD (2017) Biomedical Engineering, Chemical and Materials Engineering, University of Alberta, Canada
MSc (2012) Chemical Engineering, Bogazici University, Turkey
BSc (2010) Chemical Engineering, Yildiz Technical University, Turkey

Past Experience

Postdoctoral Fellow (2018-2020) Department of Chemical and Physical Sciences, Department of Physics, University of Toronto

Teaching activities

Current Teaching

CHME 6011 - Advanced Transport Phenomena

Publications

Journal Articles

1. Araujo, E. D., Erdogan, F., Neubauer, H., Meneksedag-Erol, D., Manaswiyoungkul, P., Eram, M., Qadree, A., Israelian, J., Orlova, A., Seo, H. S., Suske, T., Pham, H. T. T., Boersma, A., Tangermann, S., Kenner, L., Rulicke, T., Dong, A., Ravichandran, M., Brown, P., Audette, G., Rauscher, S., Dhe-Paganon, S., Moriggl, R., Gunning, P. T. Structural and Functional Consequences of the STAT5B N642H Driver Mutation. Nature Communications, 10: 2517.

2. Meneksedag-Erol, D.; Kizhakkedathu, J. N.; Tang, T.; Uludağ, H. Molecular Dynamics Simulations on Nucleic Acid Binding Polymers Designed to Arrest Thrombosis. ACS Applied Materials & Interfaces 2018, 10, 28399–28411.

3. Meneksedag-Erol, D.; Tang, T.; Uludağ, H. Mechanistic Insights into the Role of Glycosaminoglycans in Delivery of Polymeric Nucleic Acid Nanoparticles by Molecular Dynamics Simulations. Biomaterials 2018, 156, 107-120.

4.  Uludağ, H.; Landry, B.; Valencia-Serna, J.; K.C., R.B.; Meneksedag-Erol, D. Current Attempts to Implement siRNA-based RNAi in Leukemia Models. Drug Discovery Today 2016, 21, 1412-1420. 

5.  Meneksedag-Erol, D.; KC, R. B.; Tang, T.; Uludağ, H. A Delicate Balance When Substituting a Small Hydrophobe onto Low Molecular Weight Polyethylenimine to Improve Its Nucleic Acid Delivery Efficiency. ACS Applied Materials & Interfaces 2015, 7, 24822−24832. 

6. Meneksedag-Erol, D.; Tang, T.; Uludağ, H. Probing the Effect of miRNA on siRNA−PEI Polyplexes. Journal of Physical Chemistry B 2015, 119, 5475−5486.

7. Meneksedag-Erol, D.; Tang, T.; Uludağ, H. Molecular Modeling of Polynucleotide Complexes. Biomaterials 2014, 35, 7068-7076.

8. Meneksedag-Erol, D.; Dogan, A.; Kanlikilicer, P.; Ozkirimli E. Communication between the Active Site and the Allosteric Site in Class A Beta-lactamases.. Computational Biology and Chemistry 2013, 43, 1-10.

Book Chapters

1. Meneksedag-Erol, D.; Rauscher, S. Atomistic Simulation Tools to Study Protein Self-aggregation. In: McManus J. (eds.) Protein Self-Assembly. Methods in Molecular Biology, Volume 2039, 2019, 243-262. 

2. Meneksedag-Erol, D.; Sun, C.; Tang, T.; Uludağ, H. Molecular Dynamics Simulations of Polyplexes and Lipoplexes Employed in Gene Delivery. In: Prokop A. et al. (eds.), Intracellular Delivery II, Fundamental Biomedical Technologies Volume 7, 2014, 277-311.
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